'tioacetazone'这个词语来源于英语，是一种抗结核药物。常见翻译为硫醇乙酰肼，是一种常用的结核病治疗药物，其主要机理为通过抑制细菌的酶活性，阻止细菌细胞壁的合成。
以下是9个含有'tioacetazone'的例句：
1. Tioacetazone has been widely used as a second-line drug for the treatment of tuberculosis in many developing countries.（tioacetazone已被广泛用作许多发展中国家结核病治疗的二线药物。）
2. The combination therapy of isoniazid and tioacetazone has been proven to be effective in the treatment of multidrug-resistant tuberculosis.（异烟肼和tioacetazone的联合疗法已被证明在治疗多重耐药结核病方面非常有效。）
3. Tioacetazone is mainly metabolized through acetylation to form acetyl tioacetazone, which has lower toxicity than its parent compound.（tioacetazone主要通过乙酰化代谢形成乙酰tioacetazone，后者毒性低于其原始化合物。）
4. The resistance to tioacetazone has been increasing in recent years, which poses a challenge to tuberculosis treatment.（近年来，对tioacetazone的耐药性不断增加，这给结核病治疗带来了挑战。）
5. The use of tioacetazone in pregnant women should be carefully monitored due to its potential teratogenic effects.（由于tioacetazone可能具有致畸性作用，孕妇使用该药物应受到谨慎监测。）
6. Tioacetazone is often used in combination with other drugs such as rifampicin and streptomycin to maximize its efficacy.（tioacetazone常与利福平和链霉素等其他药物联合使用，以最大化其功效。）
7. The side effects of tioacetazone include skin rash, fever, and gastrointestinal discomfort.（tioacetazone的副作用包括皮疹、发热和胃肠不适。）
8. Tioacetazone has a long half-life and can remain in the body for several days after the last dose.（tioacetazone的半衰期长，最后一次剂量后可在体内停留数天。）
9. The development of new drugs to treat tuberculosis is urgently needed due to the increasing resistance to tioacetazone and other currently available drugs.（由于tioacetazone和其他当前可用药物的耐药性不断增加，迫切需要开发新的结核病治疗药物。）
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